DNA matching pytho coding

Cerrado Publicado Nov 3, 2015 Pagado a la entrega
Cerrado Pagado a la entrega

Matching DNA

Project Description :This project will give you more experience with while loops and if statements, and give you an opportunity to work with strings.

The Problem: Scientists measure how closely related a species is by looking at the DNA sequences for key proteins and seeing how similar/dissimilar they are. If the two sequences of DNA are essentially the same, the two species are considered to be evolutionarily closer since there is a relationship between changes and time. This process is called sequence alignment.

Consider the two strings of DNA below:

Species 1: AATAACGAAA

Species2: AAAACGAAAA

A scientist can change the alignment by assuming that an insertion or deletion, of one of the bases has occurred. They could make such a change, called an indel for short, to see if it improves the alignment:

Species 1: AATAACGAAA-

Species 2: AA-AACGAAAA

Assuming two indels, marked as two dashes(-), the alignment is greatly improved. The scientist would assume that two changes happened, one change in each species.

While complex algorithms exist to do sequence alignment, it is also useful to support a researcher and allow them to do an alignment by hand.

Project Specification

1. You will prompt for two strings. The strings can have any characters you like, but to be "biological" it should consist of: "A", "T", "C", "G". The strings do not have to be of the same length

. 2. You will then prompt for one of 3 commands: a. "a" for add. Add an indel b. "d" for delete. Delete an indel c. "s" for score. Score the present alignment d. "q" for quit. Stop the process.

3. Adding an Indel. When you add an indel, you must prompt for two pieces of information:

a. which string to change b. at what index (starting at 0) do you wish to place the indel (placement is before the given index, Error if the index is out of range). The string should then be modified and a dash(-) added.

4. Delete an Indel: If you can add an indel, you should be able to delete it if it doesn't do what you want. Again, you must prompt for two pieces of information a. which string to change b. the index (starting at 0) to delete the indel. It is an Error to delete a character that is not an indel.

5. Scoring. You will report the number of matches and the number of mismatches. a. Any indel is automatically a mismatch. b. If one string is shorter than the other, the shorter string is filled out with indels. c. After you score, you print both strings. i. Matching characters are printed in lower case. If the user entered upper case letters, you convert them to lower case on a match. ii. All mismatches are printed in upper case. iii. Indels are printed as dashes.

Python

Nº del proyecto: #8830998

Sobre el proyecto

8 propuestas Proyecto remoto Activo Dec 10, 2015

8 freelancers están ofertando un promedio de $263 por este trabajo

szymszteinsl

Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !Ready !R Más

$250 USD en 3 días
(5 comentarios)
4.1
kcaspe11

Nice to see such a clear description of the task! I like tasks like this which require a bit of logical thinking. I have great experience with problem solving in Python, and understand your task fully. I am 100 % sure Más

$322 USD en 2 días
(1 comentario)
4.2
phungkhactuhn

i have a team work, we have experience with python. I think we can help you do this project. Please contact me if you need. Thanks you

$250 USD en 5 días
(2 comentarios)
1.8
jsmith15

A proposal has not yet been provided

$250 USD en 1 día
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0.0
Loran425

sounds like a great little project. I can have a rough version running within 48 hours and can have a polished version to you with in a week and will offer the week after for if any problems arise. Guaranteed fixes f Más

$250 USD en 14 días
(1 comentario)
0.2
lprett

Hello, I'll give you reasons why should you have to choose me: - I can do it fast (time advantage); - I can do it easily (less bugs); - So it will be cheap (economic advantage); - I can give you support in case of any Más

$278 USD en 1 día
(0 comentarios)
0.0
Merrymeru

A proposal has not yet been provided

$250 USD en 5 días
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0.0